Friday, November 15, 2019
Genetic Engineering and Cryonic Freezing: A Modern Frankenstein? Essay
Genetic Engineering and Cryonic Freezing: A Modern Frankenstein? Ã Ã Ã In Mary Shelley's Frankenstein, a new being was artificially created using the parts of others. That topic thus examines the ethics of "playing God" and, though written in 1818, it is still a relevant issue today. Genetic engineering and cryogenic freezing are two current technologies related to the theme in the novel of science transcending the limits of what humans can and should do. Ã Genetic engineering is widely used today. Genetically altered bacteria are used to make human insulin, human growth hormone, and a vaccine for hepatitis B. Two vaccines against AIDS created with genetic engineering have begun clinical trials here in the United States ("The Genetic Revolution" 10), and genetic engineering is used to detect genetic defects in human fetuses ("The Controversy over Genetic Engineering" 18). Ã Many are now considering using this technology to change humans, such as developing methods that could be used to regenerate or repair faulty organs. It could be also used to find a cure for diseases such as cancer, eventually (Fitzgerald), or to repair genetic defects. Parents could choose the sex and height of their offspring and be able to have more intelligent, more athletic, and better looking children. Also, genetic engineering could also be used to clone humans (Kevles 354), a topic of much discussion of late. Ã Kevin T. Fitzgerald divided potential scenarios for using cloning technology into three categories: "Producing a clone in order to save the life of an individual who requires a transplant; making available another reproductive option for people who wish to have genetically related children, but face physical or chr... ...Victor may have succeeded in his goal of creating a new being and breaking death's hold over humankind, it appears that it will be us that puts forth the final and most acceptable solution. WORKS CITED Ã Begley, Sharon. "Designer Babies." Newsweek November 9, 1998: 61,2. "The Controversy over Genetic Engineering." Awake December 8, 1978: 18-20. Fitzgerald, Kevin T. "Little Lamb, Who Made Thee?" America March 29, 1998. . "The Genetic Revolution." Awake July 22, 1989: 10. Kevles, Daniel J. and Leroy Hood. "Will the Human Genome Project Lead to Abuses In Genetic Engineering?" Taking Sides. Ed. Thomas A. Easton. Guilford, Connecticut: Dushkin Publishing Group Inc., 1995. 342-357. Shelley, Mary. "Frankenstein." Puffin Books, Penguin Group. London, England, 1994. Pages 64-65. http://alcor.org. "Alcor Life Extension Foundation." 1998.
Tuesday, November 12, 2019
Types of Thermometer
Different types of thermometers Galileo thermometer. Aà Galileo thermometerà (orà Galilean thermometer), named after Italian physicistà Galileo Galilei, is aà thermometerà made of a sealedà glass cylinderà containing a clearà liquidà and a series of objects whose densities are such that they rise or fall as the temperature changes. By definition, Galileo's thermometer is actually a thermoscope, not a thermometer. Gas thermometer Aà gas thermometerà measuresà temperatureà by the variation in volume or pressure of a gas.One common apparatus is a constant volume thermometer. It consists of a bulb connected by aà capillary tubeà to aà manometer. The bulb is filled with a gas such that the volume of the gas in the bulb remains constant. The volume is related to temperature by k, known as Charles's Lawà . The pressure of the gas in the bulb can be obtained by measuring the level difference in the two arms of the manometer. Gas thermometers are often used to calibrate otherà thermometers. Alcohol thermometerTheà Alcohol thermometerà orà spirit thermometerà is an alternative to theà mercury-in-glass thermometer, and functions in a similar way. But unlike mercury-in-glass thermometer, the contents of an alcohol thermometer are less toxic and will evaporate away fairly quickly. For the working temperature range, themeniscusà or interface between the liquid is within the capillary. With increasing temperature, the volume of liquid expands and theà meniscusà moves up the capillary. The position of themeniscusà shows the temperature against an inscribed scale. Infrared thermometerInfrared thermometersà inferà temperatureà using a portion of theà thermal radiationà sometimes calledà blackbody radiationà emitted by the object of measurement. Theyââ¬â¢re sometimes calledà laser thermometersà if aà laserà is used to help aim the thermometer, orà non-contact thermometersà to describe the deviceà ¢â¬â¢s ability to measure temperature from a distance. By knowing the amount of infrared energy emitted by the object and itsà emissivity, the object's temperature can be determined most of the time. Mercury thermometer Aà mercury-in-glass thermometer, is aà thermometerà consisting ofà mercuryà in aà glassà tube.Calibrated marks on the tube allow theà temperatureà to be read by the length of the mercury within the tube, which varies (nearly linearly) according to the temperature of the mercury. To increase the sensitivity, there is usually a bulb of mercury at the end of the thermometer which contains most of the mercury; expansion and contraction of this volume of mercury is then amplified in the much narrower bore of the tube. The space above the mercury may be filled withà nitrogenà or it may be less than atmospheric pressure, which is normally known as aà vacuum.
Sunday, November 10, 2019
Pfizer Marketing Strategies Essay
Pfizer Inc., discovers, develops, manufacturers, and markets leading prescription medicine for humans and animals and many of the worldââ¬â¢s best-known consumer brands. Their innovative, value-added products improve the quality of life of people around the world and help them enjoy longer, healthier, and more productive lives. The company has three business segments: health care, animal health and consumer health care. The top three worldwide pharmaceutical companies in sales are from GlaxoSmithKline, Pfizer and Merck respectively. In 2001, Pfizer increased itsââ¬â¢ market share and became the sales leader. They have continued to lead the industry since. The main reason for their tremendous growth is that their pharmaceutical products are able to improve the quality of life of their customers. Those products are Aricept, Celebux, Diflucan, Lipitor, Neurontin, Norvasc, Viagra, Zithromax, Zoloft and Zyrtec. Research and development is vital to the success of any pharmaceutical company. Pfizer spent 7.1 billion on research and development in 2003; this is the only pharmaceutical company that is capable of investing this much. Their future, as one company, with a single purpose and mission, is sharply defined. Pfizer Inc. wants to be the company that does more good, for more people, than any other on the planet. Innovation is critical to improving health and sustaining Pfizerââ¬â¢s growth and profitability. They are deeply committed to meeting the needs of their customers, and we constantly focus on customer satisfaction. Pfizer is now implementing a strategy to drive performance within the global business, building on the business model and management ethic that they applied in the United States. The most important priority is to improve sales performance through the launch of new pharmaceutical products, encourage doctors to continue to prescribe existing products, and attempt to increase consumption and enlarge the over-the-counter market. Pfizer is a strong and reliable brand, with a solid competitive position and diversified product line that appeals to a wide customer base. However, Pfizer needs to communicate with their clients more effectively in order to capitalize on their opportunities. Their current objective focuses heavily on increasing profitability and sales volume of the new products, such as Lipitor,à Norvasc, Celebrex and Neurontin. They are seeking to increase efficiency by reorganizing of the structure of the company. Pfizersââ¬â¢ focus on research and development is matched by an equally strong emphasis on marketing. The company promotes its human pharmaceutical products to health care providers including doctors, nurse practitioners, physician assistants, pharmacists, pharmacy benefits managers, and managed care organizations. Pfizer also promotes its products directly to consumers in the U.S. via direct-to-consumer (DTC) print and television advertising. Pfizer has responded to the Food and Drug Administrationââ¬â¢s 1997 decision to loosen restrictions on DTC advertising of prescription drugs by increasing DTC promotional spending each year Pfizerââ¬â¢s strong marketing and sales operations have enabled the company to become the ââ¬Å"partner of choiceâ⬠for the marketing of innovative products developed by others. Pfizer is extremely skilled in creating alliances with other pharmaceutical companies via co-promotion agreements. Through co-promotion and licensing agreements, Pfizer promotes and markets such highly promising products as Celebrex, Bextra, Aricept, and so on with alliance partners. Pfizer provides cash, staff, and other resources to further develop, market, promote, and sell the products in exchange for a share of revenues. For the over-the-counter market, Pfizer advertises in newspapers, magazines and uses outside media, especially for essential pharmaceutical products. An example would be the cardiovascular medicine ââ¬Å"LIPITORâ⬠. Potential customers gain product knowledge through advertisements when reading newspapers and popular magazines. For doctors, Pfizer spends a substantial amount of money for physician-type advertisements, such as small catalogs, relevant posters, printed 3D diagram regarding the specified product because the doctor is their main customer. Once the patient is exposed to the advertisements inside the clinic, they have more product knowledge and confidence. Pfizer continues to have sales promotions each year to support the 2-3 products they develop annually. These sales promotions are focused onà hospitals and general practitioners. Before the new product is going to launch, Pfizer announces relevant details to these people first and advises them of all of the available support. Once launched, a clinical study paper and samples are delivered to the doctors when Pfizer representatives are visiting them. Antibiotics are classified into four groups: Penicillin, Quinolones, Macrolides and Cephalosporins. Patients will develop a resistance through continued use of same antibiotic, which is why Pfizer continually develops new antibiotics. Sales promotion, advertising, and product knowledge are all very important aspects of marketing for Pfizer to launch their new products. While Pfizer has a number of strong products in its portfolio, it is Viagra that has received a large amount of attention recently and its success will be important for Pfizer. However, the huge cost of Viagra has been a highly discussed issue, with a number of governments struggling to reach decisions over reimbursement issues. However, Viagraââ¬â¢s high cost may lead to the use of cheaper, alternative treatment for the condition. There have also been a number of safety issues surrounding the use of Viagra. Because of the high consumer awareness of Viagra due to extensive media coverage, the continued safety concerns, combined with the impending launch of alternative oral treatments, this could have a significant adverse affect on the sales of Viagra. Pfizer appears to have continued high expectations for Viagra, possibly implying an over dependence on the success of one product. The high sales and marketing investment by Pfizer to promote Viagra could damage the companyââ¬â¢s profitability if revenues from Viagra do not live up to expectations. Pfizer is a company that has a stronghold on itsââ¬â¢ market, due to having superior research and development department, as well as one of the most innovative ways to approaching potential customers and business partners. All of this contributes to their competitive advantage and enables the company to always stay a step ahead of their competitors. Although the health care industry is ever changing and threats and opportunities often appear, Pfizer has a stable base for the future in this business field. As the company motto states: ââ¬Å"Life is our Lifeââ¬â¢s Work!ââ¬
Friday, November 8, 2019
Risk Management Process
Risk Management Process Introduction Risk is imminent in any industry that a business organization may be operating. As a result, it is incumbent upon the management to put in place measures that will ensure adequate prevention of any possible risk. Risk management process has been defined as a process through which an organization plans and executes organizational activities with the aim of reducing or even avoiding effects of risks.Advertising We will write a custom report sample on Risk Management Process specifically for you for only $16.05 $11/page Learn More It is important, however, to note that it is capital and income of organizations that are shielded against risk. It should also be noted that for a typical risk management program to be effective, various vital components must be taken into consideration. Risk identification To begin with, it is important to note that one will be fight a futile war if the enemy is not known. Consequently, it is paramount that any risk man agement program begins by identifying which risks are most likely to occur and therefore affect the business. It is only after identification of the risk that it can be feasible to investigate causes of the risk. The risk identification step should also include the identification of events or activities of the organization that are most likely to trigger risks. The manner in which management may chose to carry out the risk identification process usually depends on the business environment, culture as well as the regulations in place. Risk Assessment Risk identification enumerates the risks that can occur, but does not say anything about the most prevalent or the most severe risk. However, for proper risk management it is important for the firm to know which risks can easily occur and which ones have the highest effects on the company assets or income. Consequently, risk assessment to categorize the possible risks according to their probability of occurrence and severity of impact is crucial. It is imperative to note that risk assessment also involves determination of the assets that are vulnerable incase a given risk occurs. However, risk assessment has one draw back which is its inability to precisely determine the pace at which various risks can occur. This is due to the unavailability of reliable statistics hence a higher degree of inaccuracy. Nevertheless, this component of risk management program is vital in assisting management to prioritize its actions. Risk Handling Risk handling involves the process by which strategies to tackle each risk are formulated and implemented. In addition, it includes the prioritization of the strategies in order to cater for the most crucial assets. The ultimate goal of any risk management program is to avoid any risk to the organization. However, it is practically impossible that risks can be completely avoided by any organization no matter how perfect the risk management program may be.Advertising Looking for repo rt on business economics? Let's see if we can help you! Get your first paper with 15% OFF Learn More As a result, the programs aim to avoid the risk if possible or transfer the risk whenever necessary to institutions or people well placed to take the risk. Nevertheless, there comes a time when the firm cannot avoid some risks. In such a scenario, the management may choose to mitigate the effects of the risk or accept the risk either partially or in full. Whichever the strategy that a firm may choose, its priority should be to safeguard the organizationââ¬â¢s capital, assets and income. Conclusion Risk management is not an easy or direct process as many may have wished it to be. Besides being influenced by uncontrollable conditions, it is clouded by a lot of uncertainties which leads to inaccuracies in decision making. Nonetheless, it is a crucial part of organization procedures and has to be undertaken. Therefore, it is upon the management of any organization to ensure that efforts are made to get the most appropriate risk management program implemented.
Tuesday, November 5, 2019
Chiral Center Definition in Chemistry
Chiral Center Definition in Chemistry Chiral Center Definition A chiral center is defined as an atom in a molecule that is bonded to four different chemical species, allowing for optical isomerism. It is a stereocenter that holds a set of atoms (ligands) in space such that the structure may not be superimposed on its mirror immage. Chiral Center Examples The central carbon in serine is a chiral carbon. The amino group and hydrogen can rotate about the carbon. While chiral centers in organic chemistry tend to be carbon atoms, other common atoms include phosphorus, nitrogen, and sulfur. Metal atoms may also serve as chiral centers. Sources Mislow, Kurt; Siegel, Jay (1984). Stereoisomerism and local chirality. Journal of the American Chemical Society. 106 (11): 3319. doi:10.1021/ja00323a043Solomons, T. W. Graham; Fryhle, Craig (2004).à Organic Chemistryà (8th ed.). John Wiley Sons.
Sunday, November 3, 2019
Jet Blue Case Study Essay Example | Topics and Well Written Essays - 1750 words
Jet Blue Case Study - Essay Example In this case, it is necessary to analyze human resource strategies, policies and practices directed toward the provision of best services within the airline industry. The following paper will examine and make an analysis of resource strategies, policies, and practices and their relation to one of the well-known low-cost U.S. carriers, JetBlue Airways. In terms of hiring practices, JetBlue follows the Equal Employment Opportunities laws through its Corporation Affirmative Action Policy, which impedes any ways of discrimination and harassment against any candidate, employee, suppliers, and customer. As one of the key companyââ¬â¢s values, Caring and Integrity in following EEO rules is doubtless (Oââ¬â¢reill & Hoffer Gittell, 2001). According to the Corporation Code of Conduct (2014), JetBlue respects individuals in a non-discriminatory manner and without regard on race, gender identity, sexual orientation and religion, age, citizenship, disabilities and such status as veteran. These are all the regulations of the company based on such laws as Age Discrimination in Employment Act of 1967, Americans with Disabilities and Rehabilitation Act of 2008 and Fair Labor Standards Act of 1958 (EEO Laws, n.d.). The process of recruitment should be aimed to not only filling with certain organizational gaps, but be focused on searching for specific skills and experiences of people to build an organization. The recruitment process at JetBlue, according to Oââ¬â¢reilly and Hoffer Gittell (2001), is the most important thing as it means to search for those who would fit company values. For internal sources, employees are at the highest concern within the company, as they know the requirements of various positions and are able to take full responsibility on such knowing and desire to hold a new job. JetBlue motivates talented crewmembers in different ways, developing its reputation for special treating of
Friday, November 1, 2019
Discription Essay Example | Topics and Well Written Essays - 500 words - 1
Discription - Essay Example The pumping of the heart is controlled by the Sino atrial (SA) node that is located in the posterior wall of the right atrium(Heart 1995). 2. The valves: there are two types of valves the Atrioventricular valves (located in the middle of the heart between the ventricle and the atria) of two types the tricuspid on the right and mitral/cuspid on the left and the Semilunar valves of two types pulmonary and the aortic valve. The functions of the valve is too prevent the backflow of blood to the chambers. 3. The vessels: There are four main vessels in the heart; the vena cava divided into superior and inferior, the pulmonary artery, the pulmonary vein and the aorta. The functions of veins is to covey blood from and to the heart. The heart is divided into four chambers: the top two chambers are known as the atriums and the bottom two chambers are called ventricles. Importantly, the atriums both contract at the same time same as the two ventricles(Heart 1995). First and foremost, deoxygenated blood enters the heart via the superior and the inferior vena cava into the right atrium. The right atrium contracts and forces the blood to rush into the right ventricle through the tricuspid valve. Consequently, when the right ventricle contracts, the deoxygenated blood is pumped into both lungs through the pulmonary arterypast the semi lunar valves(Heart 1995). The process continuesas the blood is returned from the lungs via the pulmonary veins wherethe oxygenated blood is delivered to the left atrium. When the atrium contracts the blood is rushed through the valves into the left ventricle, thestrongest and most muscular portion of the heart.When the left ventricle contracts, blood is rushed through the aort a: he aorta is the main artery leaving the heart (Lewis 1925). Through this process, oxygenated blood is now taken throughout
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